OSIRIS was a general-purpose 1-2.5 micron imager and moderate-resolution spectrometer that was the first cryogenic infrared instrument built by the OSU ISL. Originally designed to fully illuminate a 256x256 NICMOS-3 HgCdTe array with 27 micron pixels (then the largest IR array available) it was eventually retrofit to use a 1024x1024 Hawaii H1RG HgCdTe array with 18.5 micron pixels. OSIRIS had a long and scientifically productive career first on the Perkins 1.8m telescope at Lowell (1991-1998), it spent 1994 on the CTIO 1.5m telescope originally to observe the collision of Comet Shoemaker-Levy 9 with Jupiter, but stayed to execute the southern part of the OSU IR Bright Galaxy Survey. It returned to Lowell in 1995 where it was heavily used until 1998 when it was retrofit with a 1024x1024 H1RG array and moved to CTIO in 1999 where it became the facility IR imager/spectrometer on the 4-m Blanco telescope until 2004, after which it became a facility instrument at the 4.2m SOAR telescope on Cerro Pachon.  It was retired from service in 2018. Many of the technical innovations developed for OSIRIS were the basis of other IR instrument built by OSU.